LH-1808 Fully automatic Liquid Handler

LH-1808 is a full-automatic liquid handling workstation from tubes to plates, tubes to tubes or plates to plates, based on directly loading blood collection or sample tubes. Combined with the 1-/4-/8-/16-/32- channel pipetting heads and the liquid volume range of 0.5-1000µL, it can flexibly handle different sample throughput and different application, realizing the full automated process of qPCR fluorescence detection. The workstation can integrate code scanner, liquid level detection module, heater & cooler, shaker, blood component recognition module, magnetic separator.

n Pipetting precise and reliable

üthree-dimensional mechanical arm positioning precision, the accuracy of 0.1 mm

üsoftware built-in various suction and dispense method to meet various application

üaccording to different liquid viscosity, adjust the Liquid Class value to achieve accuratesuction volume

üpipetting precision: 1 µL CV ≤ 5%

nLarge deck for a wide range of applications

ü30 standard worktable positions, different functional module combination to meet different applications

üIt can be used in loading the original sample tubes, sample transfer from tubes to plates and high-throughput sample processing , decreasing the times of changing deck layout and improving the degree of automation

nAutomatically change the pipetting heads

üaccording to different liquid volume and sample throughput, you can choose single channel, 4-channel, 8-channel, 16- channel, 32-channel pipetting heads, the pipetting volume range is 0.5µL - 1 mL

üautomatically loading and unloading pipetting heads and grippers to mechanical arm.

üprocesses 1 - 96 samples in parallel depending on throughput demands

Deck layout

The workstation has 30 standard bases. The super large space and flexible deck design makes many applications. The deck can combine 4 * 24 samples collection holder and 25 standard bases to realize the experiment workflow of fluorescence quantitative detection from sample transfer from original sample tubes to plate to nucleic acid extraction to qPCR set-up. The deck of 30 standard bases can used for high throughput sample processing, such as batches of sample transfer or sample screening or NGS library preparation and etc.

Multi-functional mechanical arm

XYZ axis 3D structure, with multi-functional mechanical arm, positioning accuracy up to 0.1mm, which can meet the precise positioning of the pipette heads in the 96-well plate and the 384-well plate, and accurately grasp/move/drop the plate each time.

Automatically change the pipetting heads

The pipette precision is reliable and efficient with air displacement. The barrel of pipetting heads use high hardness, light alloy material with wear-resistant coating on the surface, which is not easy to be damaged in long-term use .

Heating & shaking module

It integrates heating and shaking functions into one, makes effective deck space, and meets the application requirements of shaking and heating at the same time.

Module with liquid level detection and barcode scanning

The barcode scanner and the liquid level detection are integrated as a whole, this compact structure design reduces the space waste. The barcode scanning and the liquid level detecting operate simultaneously to save time. The code scanner is suitable for one-dimensional code and two-dimensional code. The liquid level sensor adopts ultrasonic to detect the height of the liquid level. The software can track samples in real time and analyze the height of liquid level.

Lifting module

The structure design is clever. Four tubes as a group, the tube with highest liquid level as a reference, other three tubes are elevated through a module to make the liquid level of four tubes in the same line. It can realize 4 samples transfer in parallel with the 4-channel pipetting head.

Fully automatic PCR module

It’s the unique super-conducting thermal VCM® module from Inheco Company ODTC®. The heating performance is optimized, the temperature in all wells is consistent at all times. Temperature uniformity error between wells is within +/ -0.2k at 55 ° C, 72 ° C and 95 ° C. Horizontal removable cover seal prevents accidental infection of ODTC® instruments and completely avoids cross contamination. With flexible applications, ODTC® can meet the requirements of repeated heating and cooling required in any molecular biological workflow, and prevent the evaporation of reagents during this process, such as NGS library preparation, Sanger sequencing, any experiments with temperature change flow, various enzyme reactions, hybridization, etc.

Blood component recognition module

With one-dimensional/two-dimensional code scanner, it’s convenient for sample information tracking to avoid human input errors, supporting EXCEL sheet import and export. CCD high-definition imaging technology was adopted to automatically identify the buffy coat, separate the upper serum components without white blood cells. 24 blood samples were processed each batch, with different pipette heads to meet the requirements of different volumes transfer.

Triple temperature control module

It’s a low-cost triple closed cavity module. Chamber 2 is at room temperature, the temperature of chamber 1 can be controlled at 6℃ to room temperature, and the temperature of chamber 3 can be controlled at room temperature to 110℃. Moreover, it is a closed chamber with small temperature fluctuation. This module used for temporary storage of enzyme reagents in chamber 1, volatile substances such as alcohol or light -avoiding reagents in chamber 2, incubation of enzyme reaction in chamber 3. It’s not only reduce the equipment cost, and also realize the fully automatic process for certain biological experiments.

Technical Parameter

Dimensions (length × width × height)

1100×770×830(mm)

Weight

About 150 Kg

Deck Capacity

30

Scanning time/tube

<2.3s

Liquid level detection error

<±0.5mm

Pipette head and components

Pipetting range

0.5μL ~ 1mL

Pipetting channel

Single-/4-/8-/16-/32-channel

Adaptable tips

50μL、250μL、1mL

Cooler & Heater

4-75℃

 Shaker

100-2000 rpm

Heating & shaking module

Shaking and temperature range

Room temperature ~ 100 ℃, shaking speed: 200-2000rpm

Triple temperature control module

Heating box

Upper board: room temperature ~ 110 ℃ (± 1 ℃)

Lower board: room temperature ~ 70 ℃ (± 1 ℃)

Refrigeration box

Lower board: 6 ℃ ~ room temperature (± 4 ℃)

Normal temperature box

Room temperature

Adaptable consumables

Deep well plate,  96/384-well PCR plate

Blood component recognition module

Adapted blood collection tubes

5mL、10mL

Maximum number of samples / batch

24

Code scanning

One-dimensional code, QR code

Fully automatic PCR module

temperature range

4℃~99℃

Temperature of Upper board

30℃~115℃

Temperature uniformity error

±0.2K

Adaptable consumables

96/384-well PCR plate


Types of Pipetting head

Pipetting volumeμL

Pipetting Accuracy≤CV%)

Pipetting precision±%

70μL

1

5.0

10.0

5

3.0

6.0

25

2.0

4.0

50

1.0

2.0

250μL

10

3.0

6.0

50

1.0

2.0

150

0.5

1.5

1000μL

100

0.5

1.5

500

0.3

1.0

900

0.3

1.0